Insulin resistance, a critical factor in the development of diabetes, has been linked to chronic stress. Prolonged periods of stress can negatively impact the body’s ability to use insulin effectively, leading to higher blood sugar levels. This insulin resistance is a significant risk factor for diabetes.
A recent review titled “Molecular Mechanisms Linking Stress and Insulin Resistance” revealed that chronic stress may disrupt the body’s ability to respond to insulin properly, increasing the risk of insulin resistance and diabetes. For individuals with diabetes, high insulin resistance can limit the effectiveness of certain diabetes drugs.
Chronic inflammation is another way in which stress contributes to the development of diabetes. Inflammation can disrupt blood sugar regulation and increase the risk of diabetes. This chronic inflammation can also contribute to the progression of diabetes and worsen diabetes-related complications such as diabetic neuropathy.
Stress and overstimulation can also disrupt sleep patterns, leading to poor sleep quality, which in turn contributes to insulin resistance and increases the risk of diabetes. Research has shown that acute sleep deprivation can reduce insulin sensitivity in healthy individuals without significant changes in cortisol levels, highlighting the important role that sleep plays in preventing diabetes.